Heart Rate Variability as Reactivity in Alcoholics an Index of Cue
نویسندگان
چکیده
Background: Autonomic responses fol low exposure to conditioned stimuli such as contextual factors associated with alcohol ingestion. Heart rate variabili O, is under autonomic control and may be a measure o f such response. Methods: Twenty alcoholics and 23 matched social drinkers (all male) were exposed to a neutral cue and then an ah'ohol cue in identical settings, during which the electrocardiogram o f these subjects was recorded. Time and frequency domain parameters o f heart rate variability (HRV) were computed by a blind rater. Resul ts : Coefficient o f variation ~( R-R intervals and absolute powers" o f HRV spectrum (in frequency bands 0 .05-0.15 Hz and 0.01-0.05 Hz) Jbllowing alcohol cue were significantly higher in alcoholics than social drinkers'. The mean heart rate (MHR). f i l i led to reflect this d~[fl, rence. Conclusions: HRV paradigm appears more sensitive than MHR to measure cue reactivity. Biol Psychiatry 1998; 43:544--546 © 1998 Society o f Biological Psychiat O,
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